Endocrine Abstracts

BackgroundAdrenal incidentaloma (AI) is an adrenal mass discovered accidentally during abdominal or chest imaging techniques not aimed to adrenal gland assessment. The management of non-functional adrenal adenomas (NFAI) at least 4 cm is still a matter of debate as it is unclear whether imaging can be used to characterize their potential malignancy. Moreover, the risk of new hypersecretion in nonoperated tumors is uncertain. Our aim was to better charact...

Aim: To investigate the possible association of the rs9939609 polymorphism in the FTO gene with obesity in the Republic of Tatarstan (RT).Materials and methods: The study involved 63 adult patients (21 men and 42 women; 38–77 years old) with overweight or obesity and 515 healthy young people (157 men and 358 women; 16–35 years old) with normal weight. We assessed clinical and biochemical parameters (blood lipid profile). The analysis of the rs9...

Aim: To investigate the possible association of the FTO gene rs9939609 polymorphism with different disorders of carbohydrate metabolism in residents of the Republic of Tatarstan.Materials and methods: A total of 237 patients with a single history of hyperglycemia were examined. They underwent an oral glucose tolerance test on a BS-200E Mindray analyzer. 198 patients from the whole cohort had various disorders of carbohydrate metabolism, so they were incl...

Aim: To investigate the effect of the standard dietary recommendations in diabetes mellitus type 2 to the intensity of metabolic processes due to different variants of polymorphism rs1801282 Pro12Ala of the PPARG gene.Materials and methods: 37 patients (11 men and 26 women) in the age of 38–76 years old (the mean age 56.8±9.55 y.o.), with the verified diagnosis of diabetes mellitus type 2 (the mean duration of illness 5.7±3.59 years) and t...